What are those cilia doing in the neural tube?
نویسندگان
چکیده
منابع مشابه
Mutations in the Motile Cilia Gene DNAAF1 Are Associated with Neural Tube Defects in Humans
Neural tube defects (NTDs) are severe malformations of the central nervous system caused by complex genetic and environmental factors. Among genes involved in NTD, cilia-related genes have been well defined and found to be essential for the completion of neural tube closure (NTC). We have carried out next-generation sequencing on target genes in 373 NTDs and 222 healthy controls, and discovered...
متن کاملWhat is type VI secretion doing in all those bugs?
The identification of bacterial secretion systems capable of translocating substrates into eukaryotic cells via needle-like appendages has opened fruitful and exciting areas of microbial pathogenesis research. The recent discovery of the type VI secretion system (T6SS) was met with early speculation that it too acts as a 'needle' that pathogens aim at host cells. New reports demonstrate that ce...
متن کاملTesticular leukocytes: what are they doing?
Leukocytes, specifically macrophages, lymphocytes and mast cells, are found within the testes of most, if not all, mammals. In some species (for example, rats, mice and humans), the number of 'resident' testicular macrophages, in particular, is quite considerable. However, reproductive biologists are only beginning to explore the characteristics and possible biological significance of these cel...
متن کاملWhat are hospitals doing about clinical guidelines?
OBJECTIVES To assess the attitudes of senior hospital staff towards clinical guidelines, and to ascertain the perceived extent and benefits of their local use; to identify those hospitals with current or planned future written strategies for the systematic development of clinical guidelines, and the staff responsible for leading them; and to establish the essential elements of existing strategi...
متن کاملInflatable splints--what are they doing?
The pressure to which splints were inflated was measured to determine whether splintage was effective and if vascular complications were likely. The prevalence of their use by the ambulance service was also investigated. The findings indicate that inflatable splints are in common use, and are rarely inflated to pressures likely to cause vascular complications. However, they are extremely ineffi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cilia
سال: 2012
ISSN: 2046-2530
DOI: 10.1186/2046-2530-1-19